![]() Such pathology is found in 1 in 1000 first-trimester pregnancies. Changes are common in both the placenta and the foetus. The cause of the pathology is an additional set of all chromosomes. In adulthood, these girls are often infertile. These girls are prescribed growth hormone therapy in childhood and hormone replacement therapy during puberty. Girls with X monosomy are shorter than their peers, some have kidney or heart defects, and some have difficulty learning. This syndrome occurs only in girls - 1 in 5000 live births. The cause of the pathology is a missing X chromosome. Most of these babies survive for less than a year. Most babies with trisomy 13 have multiple congenital brain and internal organ defects. The Patau syndrome is characterized by severe mental retardation. The incidence of trisomy 13 is 1 in 22,700 live births. The cause of the pathology is an excess chromosome 13. Children who do survive beyond that age have severe mental, growth, and developmental retardation. Most of the babies survive for less than a year. ![]() Foetal growth retardation occurs during pregnancy, often resulting in miscarriage, premature birth, or stillbirth. Children with this syndrome have severe damage to the brain, heart, and other internal organs. Edward’s syndrome is characterized by severe mental retardation. The incidence of Edward’s syndrome is 1 in 7500 live births. The cause of the pathology is an excess chromosome 18. Some patients with this syndrome have hearing or vision problems. Individuals with Down syndrome have a reduced IQ up to 50 and may have congenital heart and other organ defects that could require surgery. The incidence of Down syndrome is 1 in 830 live births. This is the most frequent pathology that results in genetically induced mental retardation. The cause of the pathology is an excess chromosome 21. It is important that the results are unchanged - they will be in English.Ĭhromosomal abnormalities detected during the examination: The results are received by the person/-s specified in the referral or testing request (physician and/or patient).Results will be available in about 13 working days,.Samples on the same day (or the next day at the latest) are sent to USA, where test is performed,.We need 2 tubes of maternal peripheral blood and completed documentation (referral and/or test consent form),.The test is not informative in cases of pregnancy with so-called vanishing twins or pregnancies with more than 2 foetuses, as well as twin pregnancies that have occurred through egg donors. These parameters are not included in any other NIPT tests, which in turn can increase false positives and false negatives results. Possibility of X monosomy for each twin.Individual calculation of the foetal fraction for each twin.In the test, in addition to the above-mentioned, also the following parameters are tested, which will make it easier for the gynaecologist to manage the pregnancy: Pregnancy as a result of artificial insemination (IVF)Īnd for every pregnant woman who wants to use a safe method to test the health of her unborn baby.Biochemical test or USS results deviate from what is normal for the stage of pregnancy.The woman has a history of pregnancies with trisomies.Higher PPV (positive predictive value) = less stress to the patient. Compared to the first-trimester screening, NIPT has a higher sensitivity and a significantly lower number of false-positive results in determining the most common aneuploidies.“Panorama” does not pose a risk to the baby compared to, for example, amniocentesis. ![]() The test was evaluated in 23 comparative studies of more than 1.3 million pregnancies.More than 2 million women in more than 60 countries have specifically chosen “Panorama”.The most important thing in any pregnancy is reliability “Panorama” can be performed in single, twin, artificial fertilisation, and surrogate mothers. “Panorama” test has the highest sensitivity to 22q11.2 deletion syndrome, which can affect all pregnancies in the same proportion, regardless of the mother’s age “Panorama” is the only NIPT in which zygosity, sex of both foetuses, and individual calculation of the foetal fraction for each twin (dizygotic twins) can be observed during twin pregnancy “Panorama” is the only test that distinguishes between maternal and foetal DNA, which helps to avoid false positives and false negatives “Panorama” Down syndrome screening results are more than 99% accurate “Panorama” detects conditions that other tests can’t, including molar pregnancy, triploidy, and the vanishing twin Advantages of NIPT “Panorama” over other non-invasive prenatal pregnancy screening (NIPT) tests:
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